
Nasolabial folds, commonly known as smile lines, are a natural yet increasingly prominent sign of aging caused by the loss of collagen and volume in the skin. If you’re over 30 and looking for a non-surgical solution to restore a smoother, more youthful appearance, nasolabial fold filler is a highly effective option. This guide covers everything you need to know, from the science behind the folds and essential preparation steps to choosing the best filler product for your unique facial structure.
List of contents
- Overview of Nasolabial Folds
- Anatomy and Function
- Aging and Nasolabial Folds
- Get to Know Nasolabial Fold Fillers
- Nasolabial Fold Filler Preparation Guide
- The Best Nasolabial Fold Fillers
- Neuramis
- Restylane
- Juvederm
- Summary of Nasolabial Fold Fillers
Overview of Nasolabial Folds
Nasolabial folds, often referred to as smile lines, are the prominent lines that extend from the sides of the nose to the corners of the mouth. These structures are a natural part of facial anatomy, contributing to facial expressions. Various factors contribute to the formation of nasolabial folds, including age, genetics, and environmental influences. As individuals age, skin elasticity decreases, causing these folds to become more pronounced. The reduction of collagen and hyaluronic acid in the skin leads to volume loss, further deepening these lines.
In demographics, nasolabial fold fillers are increasingly sought after among adults, particularly those over 30, who seek to reduce their appearance and enhance facial aesthetics. Clinical data indicate that non-surgical filler treatments have become a popular option due to their effectiveness and minimal downtime.
Anatomy and Function
The anatomy of nasolabial folds encompasses various facial muscles, connective tissue, and fat pads. Understanding this intricate structure is essential for professionals using fillers, ensuring natural results that respect a person’s unique facial geometry. The nasolabial area plays a vital role in facial expressiveness, facilitating movements that convey emotions.
Aging and Nasolabial Folds
Aging significantly impacts nasolabial folds. Research highlights that around 30% of individuals experience noticeable change in skin elasticity by the age of 3540. This decline causes the folds to deepen as the face loses volume. Strategies for managing these effects often involve nasolabial fold fillers, which can restore youthful contours effectively.
In combining artistry with medical knowledge, doctors can achieve enhanced patient satisfaction and natural-looking results. By addressing these age-related changes, individuals can maintain confidence in their appearance throughout their lives.
Get to Know Nasolabial Fold Fillers
Nasolabial fold fillers are a popular type of dermal filler used to treat the lines that extend from the sides of your nose down to the corners of your mouth. Often informally referred to as “nasal fold fillers,” this treatment targets the deep wrinkles, visible lines, and sagging in this area that can contribute to an aged appearance.
The injection works by restoring lost volume, which effectively smooths out the nasolabial folds for a more even and youthful look. This treatment provides both an immediate reduction in existing wrinkles and a preventative benefit by helping to keep new lines from setting in permanently.
Nasolabial Fold Filler Preparation Guide
A bit of preparation can go a long way in ensuring your nasolabial fold filler experience is both smooth and successful. By following a few simple steps, you can help minimize the risk of bruising and swelling, leading to better final results.
- Avoid Blood-Thinning Medications and Supplements: Stop taking supplements like fish oil and Vitamin E about one week before your appointment. If you take any anti-inflammatory or other blood-thinning medications (like Aspirin or Ibuprofen), you must inform your doctor.
- Stay Away from Alcohol: Refrain from consuming any alcoholic beverages for at least 1 to 3 days prior to your procedure, as alcohol can increase the likelihood of bruising.
- Disclose Your Medical History: It is crucial to tell your doctor about any underlying health conditions, allergies, or past reactions to medications or previous fillers. This ensures the procedure is completely safe for you.
Following these preparation steps is key to setting yourself up for a comfortable procedure and achieving beautiful, satisfying results.
The Best Nasolabial Fold Fillers

Choosing the best filler for your nasolabial folds should always be done in consultation with a skilled doctor. The ideal product depends on your unique anatomy, the depth of the creases, and the aesthetic goals you wish to achieve.
Here are some of the most trusted and commonly used brands for this treatment, broken down by type:
Neuramis
- Neuramis Deep Lidocaine: Features a medium-dense consistency that is easy to mold, making it versatile for various facial areas. It includes lidocaine for improved patient comfort.
- Neuramis Volume Lidocaine: A thicker and more stable option, perfect for filling deep nasolabial folds and adding volume to the cheeks. It also contains lidocaine.
Restylane
- Restylane Classic: A medium-firm filler with larger particles, best suited for treating moderate to deep wrinkles.
- Restylane Lyft: A firmer, more structured, and longer-lasting product that is an excellent choice for those needing significant volume and lift.
Juvederm
- Juvederm Voluma: Known for its firm, flexible, and durable consistency, which makes it easy to sculpt and create defined structure.
- Juvederm Volift: Offers a smoother, finer texture that hydrates the skin and delivers a very natural-looking result, making it ideal for patients with thinner skin.
Summary of Nasolabial Fold Fillers
Nasolabial folds, or smile lines, are a natural part of facial anatomy, but they become more pronounced with age, often starting in the 30s, due to the loss of collagen and skin elasticity. Nasolabial fold fillers have emerged as a highly popular non-surgical option to address this.
This treatment works by restoring lost volume, effectively smoothing the folds and contributing to a naturally youthful facial contour. Proper preparation—such as avoiding alcohol and blood-thinning supplements—is crucial for minimizing bruising and ensuring a smooth experience.



